Biomarker & air pollution

Air pollution caused up to 8.9 million premature deaths with cardiovascular diseases as the primary cause. Although the air pollution level in the U.S. is at the lower end worldwide, millions of U.S residents travel to a country with severe air pollution every year, and it remains unclear whether a short-term visit to polluted areas causes any adverse health effects. To fill this knowledge gaps, we performed a natural experiment on a group of international travelers and biomonitored their exposures to air pollutants and the subsequent health effects.


1. Yan Lin, Xinghua Qiu, Jinming Liu, Chi-Hong Tseng, Patrick Allard, Jesus A. Araujo, and Yifang Zhu, “Different temporal trends of exposure to Bisphenol A among international travelers between Los Angeles and Beijing”, 2020, Environment International,

2. Yan Lin, Gajalakshmi Ramanathan, Yifang Zhu, Fen Yin, Nolan D Rea, Xinchen, Lu, Chi-Hong Tseng, Kym F Faull, Alexander J Yoon, Michael Jerrett, Tong Zhu, Xinghua Qiu, and Jesus A Araujo, “Pro-Oxidative and Proinflammatory Effects After Traveling From Los Angeles to Beijing: A Biomarker-Based Natural Experiment”, 2019, Circulation, 2019;140:1995–2004. DOI: 10.1161/CIRCULATIONAHA.119.042054. PMID: 31744317..

3. Yan Lin, Xinghua Qiu, Yiqiu Ma, Junxia Wang, Yusheng Wu, Limin Zeng, Min Hu, Tong Zhu, and Yifang Zhu, “A novel approach for apportionment between primary and secondary sources of airborne nitrated polycyclic aromatic hydrocarbons (NPAHs)” 2016, Atmospheric Environment, 138, 108–113,

4. Yan Lin, Xinghua Qiu, Nu Yu, Qiaoyun Yang, Jesus Araujo, and Yifang Zhu “Urinary Metabolites of Polycyclic Aromatic Hydrocarbons and the Association with Lipid Peroxidation: A Biomarker-Based Study between Los Angeles and Beijing” 2016, Environmental Science and Technology, 50 (7) :3738-45. DOI: 10.1021/acs.est.5b04629, PMID: 26913796.